LITMUS Molecular Design (LMD)creates and characterizes new molecular entities.
LMD's technology, LITMUS Spectral Modeling, is a patented method of accurately predicting a molecule's:
- Chemical reactivity
- Biological activity
- Receptor binding affinity
- Toxicity, carcinogenicity
- Metabolism
- Absorption/through-membrane transmission,
- and chemical and physical properties,
based upon spectral information.
Developed at FDA's National Center for Toxicological Research (NCTR), LITMUS Spectral Modeling represents a "disruptive" technology which produces significantly more accurate results than Quantitative Structure Activity Relationships (QSAR) and Combinatorial Chemistry/High-Throughput Screening; currently the two most widely used methodologies. In side by side tests, LITMUS Spectral Modeling’s predictive accuracy proved to be 80-96% compared to 30-60% predictive accuracy for QSAR.
LITMUS Molecular Design’s value proposition is to enable pharmaceutical companies, chemical manufacturers, and herbicide and pesticide manufacturers to:
- Identify promising new compounds
- Predict efficacy or toxicity of new compounds
- Modify existing compounds to be more effective/less toxic
- Expedite introduction of drugs/NCEs
- Reduce time/cost of new drug/chemical development significantly
INNOVATE. NOT RENOVATE.
