Site Search
Skip navigation

LITMUS Molecular Design (LMD)creates and characterizes new molecular entities.

LMD's technology, LITMUS Spectral Modeling, is a patented method of accurately predicting a molecule's:

  • Chemical reactivity
  • Biological activity
  • Receptor binding affinity
  • Toxicity, carcinogenicity
  • Metabolism
  • Absorption/through-membrane transmission,
  • and chemical and physical properties,

based upon spectral information.

Developed at FDA's National Center for Toxicological Research (NCTR), LITMUS Spectral Modeling represents a "disruptive" technology which produces significantly more accurate results than Quantitative Structure Activity Relationships (QSAR) and Combinatorial Chemistry/High-Throughput Screening; currently the two most widely used methodologies. In side by side tests, LITMUS Spectral Modeling’s predictive accuracy proved to be 80-96% compared to 30-60% predictive accuracy for QSAR. 

LITMUS Molecular Design’s value proposition is to enable pharmaceutical companies, chemical manufacturers, and herbicide and pesticide manufacturers to:

  • Identify promising new compounds
  • Predict efficacy or toxicity of new compounds
  • Modify existing compounds to be more effective/less toxic
  • Expedite introduction of drugs/NCEs
  • Reduce time/cost of new drug/chemical development significantly

INNOVATE. NOT RENOVATE.


Global Technology Innovators

It is our mission to revolutionize molecular design by dramatically improving efficiency and predictive accuracy, while substantially reducing the time and costs of the development and commercialization of new molecular entities.